Thursday, August 22, 2019

Nursing research Essay Example | Topics and Well Written Essays - 250 words - 50

Nursing research - Essay Example Mainz identifies structural indicators as those indicators that describe the nature and sum of resources that a healthcare facility utilizes in the delivery of services and programs with these indicators related to the availability of a presence of human resources and material resources that have the potential of improving the quality of care (524). In line with this, it is evident that one quality improvement measure in a healthcare facility is the structural component of the healthcare facility since the structure of the facility is important in providing quality services to patients. Consequently, potential indicators related to the healthcare facility’s quality improvement measure, which is structural in nature, range from the technology used by the facility to professionals working in the facility. Mainz identifies these potential indicators as the proportion of doctors to other specialists, the healthcare facilities access to specific technology such as MRI scans, and ac cess to particular units that promote the provision of quality care

All About Writing Topics Essay Example for Free

All About Writing Topics Essay An essay is a short piece of writing on a topic and presents the authors point of view on the matter. It is a pure non-fiction presentation of the writer’s outlook on the topic that is the focus of the essay.1 An essay should be structured in different sections that make it easy for the readers to read and follow the authors thoughts clearly. It is composed of the introductory paragraph, supporting paragraphs and the summary paragraph. The introductory paragraph is the first paragraph of an essay. It brings the main idea of the essay. It captures the interest of the reader and notifies why the topic is important. Another important part of an essay is the main body or the supporting paragraphs. In these paragraphs, the main idea is discussed. The points are cited one by one to develop the main idea of the essay. Aside from the introductory and supporting paragraphs is the summary paragraph which comes at the end of the essay. In this paragraph, all the ideas in the supporting paragraph are explained through a conclusion. By reading this part alone, the reader should be able to understand the whole idea of the essay.2 Since an essay can describe, clarify, argue or analyze, it has different types.3The four major types of essays are narrative, descriptive, expository and persuasive essays. In a narrative essay, the writer tells a story about a real-life experience. When writing this type of essay, writers should try to involve the reader by making the story as vivid as possible. A well-crafted essay builds towards a conclusion or making a personal statement. The second major type on the other hand which is the descriptive essay, paints a picture with words. A writer might describe a person, place, object, or even memory of special significance. The descriptive essay strives to communicate a deeper meaning through the description. This uses colorful words and sensory details. The third type is the expository essay. This essay is an informative piece of writing that presents a balanced analysis of a topic. Moreover, in this type of essay, the writer explains or defines a topic, using facts, statistics, and examples. Lastly is the persuasive essay. While like an expository essay in its presentation of facts, the goal of the persuasive essay is to convince the reader to accept the writer’s point of view or recommendation. In this type of essay, the writer should present all sides of the argument, but must be able to communicate clearly and without equivocation why a certain position is correct.4 Despite having many types of essays with various compositions, they have one thing in common. All essays are collection of interesting ideas which are thoroughly organized to assure that readers are able to fully understand the main ideas of the essays. 1 â€Å"What is an essay,† http://www.essaycapital.com/what_is_an_essay.htm. 2 â€Å"Parts of an Essay,† http://www.customessaypaper.com/essay-help/parts-of-an-essay.htm. 3 Grace Fleming, â€Å"What is an Essay,† http://homeworktips.about.com/od/collegeprepglossary /g/essay.htm. 4 â€Å"Types of Essays: End the Confusion,†http://www.time4writing.com/writing-resources/types-of-essays/.

Wednesday, August 21, 2019

Functional Multi-enzyme Complexes In Vitro

Functional Multi-enzyme Complexes In Vitro Molecular self-assembly offers a method of sophisticated materials constructed with precision. Designing self-assembling enzyme structures is of particular interest for the unique functional capabilities of enzymes, as shown in Figure 2. Chemically induced assembly has been shown to be a powerful tool for the investigation of cellular events and for its easy operation and low cost compared to bioconjuction. Chemical inducers can be cofactors, inhibitors, metal ions, which are based on specific interaction of molecule and enzyme. Chemical inducers bring the two enzymes together to form multi-enzyme. A number of reviews have covered the self-assembly of proteins and enzymes by chemicals. King N.P. et al discussed the principles employed in recent efforts to design complex and geometrically specific protein assemblies, with a focus on practical approaches. However, precise manipulation of protein self-assembly behavior in vitro is still a great challenge. Here we review recent studies i n the chemical induced self-assembly of multi-enzyme system from the perspective of multi-enzyme complex organization, enzyme interactions, and regulation of assembly. Inhibitor induced multi-enzyme assembly Inhibitor induced dimerization has been reported as the controlled dimerization of proteins via dimerizers. During the process of dimerization, the dimerizers assemble proteins into homospecific or heterospecific multivalent nanostructures. An enzyme inhibitor binds with enzymes specifically and decreases their activity. Drug discovery typically focus on the identification and design of inhibitors to perturb enzyme function, which greatly depend on the chemical structure. Carlson and co-workers reported self-assembly of wild-type Escherichia coli dihydrofolate reductase (DHFR) into protein nanorings using dimeric methotrexate molecules, which tethered together by a flexible peptide linker. The enzymes are capable of spontaneously forming highly stable cyclic structures with diameters ranging from 8 to 20 nm. The nanoring size is dependent on the length and composition of the peptide linker, on the affinity and conformational state of the dimerizer, and on induced protein-protein interactions. Chou reported the preparation of dihydrofolate reductase (DHFR)-histidine triad nucleotide nanorings by chemically induced self-assembly. DHFR molecules with fused peptide chain of variable length were spontaneously self-assemble into protein macrocycles after treatment with a dimeric enzyme inhibitor, Bis-MTX-C9. The ring size, ranging in size from 10 to 70 nm, was dependent on the length and composition of the peptide linking the fusion proteins. The enzymatic efficiencies for the monomer and intramolecular macrocycle were found to be nearly identical, while the larger dimeric nanoring was found to have a modestly lower kcat/Km value. The nanorings catalytic efficiency was dependent on ring size, which indicated that the arrangement of supermolecular assemblies of enzymes may be used to control their catalytic parameters. However, the activator used for multi-enzyme assembly has not been reported before, which can greatly improve enzyme activity and may have greatly potential in mu lti-enzyme biosynthesis. Cofactor induced multi-enzyme assembly Cofactor-dependent enzymes, such as oxidoreductases and transferases, intramolecularly assembly of enzyme subunits by cofactor binding have been widely reported. Cofactor as a small molecular for enzyme catalysis. Cofactors can also be used for inducing multi-enzyme assembly. Bis-NAD+ has been reported for affinity precipitation of dehydrogenases in 1980s. Mansson et al used bis-NAD+ analogue to locate lactate dehydrogenase and alcohol dehydrogenase face to face and then cross-linked of the two enzymes with glutaraldehyde on agarose beads. The study of site-to-site directed immobilization effect improve the NADH production from 19% to 50%, which indicated that the NADH was preferentially channeled to lactate dehydrogenase due to the positioned active sites of the two enzymes. Similar work reported by Siegbahn as the bi-enzyme complex was formed by crosslinking lactate dehydrogenase and alcohol dehydrogenase with glutaraldehyde, which indicated an enhancement of 1.36 fold of the NADH regeneration when lactate dehydrogenase and alcohol dehydrogenase were site-to-site oriented. Cofactor induced assembly can form the site-to-site oriented structure, has the advantage easy operation and maintains the enzymes’ activity maintain. However, the interaction of NAD+ with enzyme is relatively low. Cofactor analogues have been reported for enzyme catalysis, which have the advance of low cost and high stability. The improvement of cofactor analogues for multi-enzyme assembly is promising. Metal ions induced multi-enzyme assembly Metal ions guide proteins into forming large assemblies, which provide a wide platform to modulate the metal coordination environment through distant, noncovalent interactions, exactly as natural metalloproteins and enzymes do. Metal ions in metalloenzymes located in the pocket whose shape fits the substrate, which are usually coordinated by nitrogen, oxygen or sulfur centers belonging to amino acid residues. Since approximately half of all proteins contain a metal ion, metal ions induced enzyme assembly is a promising method. Metal ions induced protein assembly is recently hot topic. There are two main types of metal ions induced protein assembly, namely, metal ions chelating sites on the artificial His-tags of enzymes and chelating sites on the surface of enzymes. His-tagging is the most widespread strategy to purify recombinant proteins. With the addition of 4-10 poly-histidine tag to the N terminus or C terminus of a target protein, the tagged protein purification was achieved by immobilized metal affinity chromatography. Multi-enzyme complex were formed with the Ni2+ and bis-His coordination of GDH-NOX fused enzymes, which enhanced enzyme activity and stability for the biosynthesis of DHA from glycerol with cofactor regeneration.. Chelating sites on the surface of enzymes The metal ions coordinated with the chelating sites on the surface of proteins was reported. Chelating sites should be on the surfaces to coordinate with metal ions, and the interfaces where chelating sites are located should be complementary to form stable self-assemblies. Yushi Bai, et al [Bai, Y.S. et al. Highly ordered protein nanorings designed by accurate control of glutathione S-transferase self-assembly. J Am Chem Soc 135, 10966-10969 (2013). ]reported a variant of glutathione S-transferase (sjGST-2His) which has two properly oriented His metal-chelating sites on the surface self-assembled in a fixed bending manner to form protein nanorings. The accurate orientation of proteins and self-assembly was based on metal-ion-chelating interactions and nonspecific protein–protein interactions. This work provides a de novo design strategy for the construction of novel protein superstructures. The self-assembly of glutathione S-transferase into nanowires was also reported[Zhang, W. et al. Self-assembly of glutathione S-transferase into nanowires. Nanoscale 4, 5847-5851 (2012).]. Designed metal coordination interactions to arrange enzyme into highly ordered supramolecular architectures has been reported recently[Salgado, E.N., Radford, R.J. Tezcan, F.A. Metal-Directed Protein Self-Assembly. Accounts Chem Res 43, 661-672 (2010).].Enzymes represent particularly attractive building blocks due to their chemical and structural versatility, for new and improved supramolecular properties. Metal-directed enzyme self-assembly yields stable architectures and high catalysis efficiency. These emergent physical and functional properties are attained with minimal modification of the original building blocks Brodin reported the self-assembly of a designed variant of cytochrome cb(562) by zinc ion coordination to uniform 1D nanotubes or 2D arrays with very high chemical stabilities. Their metal-mediated frameworks was used as the templated growth of small Pt-0 nanocrystals. [Brodin, J.D., Carr, J.R., Sontz, P.A. Tezcan, F.A. Exceptionally stable, redox-active supramolecular protein assemblies with emergent properties. P Natl Acad Sci USA 111, 2897-2902 (2014).] Bogdan et al reported [Bogdan, N.D. et al. Metal Ion Mediated Self-Assembly Directed Formation of Protein Arrays. Biomacromolecules 12, 3400-3405 (2011).] the self-assembled inorganic–protein arrays by FeII complexation of protein-conjugated terpyridine units (ligand) to form well-defined and controllable size and structure. Residue-specific conjugation between the complexing unit (terpy) containing an activity-based probe and a corresponding active enzyme (papain) performed on this unique building block (ligand) leads to chemical species of unprecedented constitution. Metal ion induced assembly are controllable by environmental factors that affect the coordination or reactivity of the metal ion: the presence of the metal itself, external chelators, pH, and the solution redox state. Thus, metal ions can augment or provide all three essential properties of proteins as nature’s favorite build-ing blocks: structure, chemical reactivity, and stimuli- responsiveness. Metal ions are frequently found in natural protein-protein interfaces, where they stabilize quaternary or supramolecular protein structures, mediate transient protein-protein interactions, and serve as catalytic centers. Paralleling these natural roles, coordination chemistry of metal ions is being increasingly utilized in creative ways toward engineering and controlling the assembly of functional supramolecular peptide and protein architectures. Here we provide a brief overview of this emerging branch of metalloprotein/peptide engineering and highlight a few select examples from the recent literature that best capture the diversity and future potential of approaches that are being developed. Conclusions and Outlook Constructing functional multi-enzyme complexes in vitro by mimicking the natural enzyme complex has great biotechnological potentials in metabolic engineering, multi-enzyme-mediated biocatalysis, and cell-free synthetic pathway biotransformation. This review summarizes chemically assembling of multi-enzymes based on the affinity included by small molecular, namely, cofactor, substrate, inhibitor, and metal ions, et al. Distinctions were made based on the assembling driving force, structure of multi-enzyme complexes and mechanism of catalytic efficiency enhancement. Furthermore, the current challenges of multi-enzyme assembly in vitro induced by chemicals was addressed and gave an outlook on future developments. In this review, a classification of multi-enzyme assembly methods is proposed. Special emphasis is placed on the description of constructing functional multi-enzyme complexes by small molecular induced self-assembly. Assembling of multi-enzymes based on the affinity induced by small molecular, namely, cofactor, inhibitor, and metal ions were discussed. Furthermore, the advantage and disadvantage of each method from the reaction and process considerations are described. A variety of approaches for multi-enzymatic synthesis in vivo using biological systems or in vitro with isolated biocatalysts have been successfully used for the synthesis of complex molecules, especially the chiral chemicals which frequently are not readily accessible by chemical synthesis. In the long term, multi-enzyme processes will replace many chemically catalyzed processes. Biocatalysis today is growing not only in the fine chemicals and pharmaceuticals but also in the production of bulk chemicals. The relevant multi-enzyme catalysis processes have a significant potential for industrial application. Several challenges remain for multi-enzyme processes despite the strong drivers for greener and ever more effective chemical process technology.Multi-enzyme assembly into exquisite, complex, yet highly ordered architectures is challenging due to the complexity of enzyme structures and interactions. Consequently, the prediction of multi-enzyme complex configurations, the structure controlled assembly and the dynamic kinetic simulation of assembly process are also challenging. Current efforts aim at the prediction of multi-enzyme complex configurations as well as at nanoscale reconstruction, and control of cascade reaction. The design of multi-enzymatic systems based on the structure controlling and function prediction. In Nature’s hierarchy such design and engineering studies can provide useful information. New approaches that allow the controlled assembly of multiple enzymes at a nanometer scale with precisely structure and function will increase reaction rates and the efficie ncy of longer synthetic enzymatic cascades. Another frontier in multi-enzyme synthesis is the design of multi-step processes, involving mathematical modeling, process technology, and protein engineering. By viewing multi-enzyme assembly process in terms of structure and function relationship, it is possible to unify a diverse range of investigations, highlights their interrelationships, and see routes.

Tuesday, August 20, 2019

Celebrity Endorsement on Rural Consumers

Celebrity Endorsement on Rural Consumers The celebrities in India are the role models for majority of Indians, they are so influenced by them that most of the population follows the trends of their dressing, styles and habits. This is the major reason for the companies to hire the celebrities to promote their products. The companies invest billions of to hire the celebrity for the promotion of their product. The companies believe that the celebrity changes the purchase intention of the consumers in India. The study is conducted to find out the impact of celebrity on rural consumers of Lucknow district of Uttar Pradesh. In order to analyze the objective of the study the data was collected using convenience sampling from 300 respondents belonging to the randomly selected areas of Lucknow. The secondary data was collected through different sources such as- Journals, Magazines, Internet, and Newspaper etc. Null hypothesis was framed and analytical Techniques are the statistical tools that are used for analyzing the collected da ta. The frequency tables were used to represent the collected data. One sample T-test was used to test the hypothesis and ANOVA was used to calculate the significance level of impact of celebrity endorsement on rural consumers. The SPSS 17 is also used as statistical software to analyze the collected data. It is found that the Indian consumers prefer celebrities in the television commercials. Keywords Brand Building, Brand Promotion, Celebrity Endorsements, Indian Television Commercials. INTRODUCTION The celebrities in India are the role models for majority of Indians, they tries to follow their styles, clothes and their small habits. Celebrity endorsement is most acceptable and common phenomenon that companies use to attract their consumers across the world. They believe that celebrities can influence the purchasing decision of their prospect consumers as they have special places in the heart of consumer. Therefore after analyzing the degree of involvement to follow the celebrities, the companies started hiring various bollywood and sports stars for the commercial advertisements. That is why the promotional budget for advertising has taken many financial folds compared to past investments. The companies invest billions of Rupees over hiring a celebrity for their product promotion. Such endorsers are seen as dynamic with both attractive and likeable qualities and companies plan that these qualities are transferred to products via marcom activities. Furthermore, because of their f ame, celebrities serve not only to create and maintain attention but also to achieve high recall rates for marcom messages in todays highly cluttered environments. Theory and practice prove that the use of super stars in advertising generates a lot of publicity and attention from the public (Ohanian 1991). Therefore, Celebrity endorsement has been established as one of the most proffered tools of advertising. It has become a trend and perceived as a winning formula for product marketing and brand building. It is very easy to have a celebrity for a product or brand but it is very tough to establish a very strong association between the product and the endorser: because the objective is to build a brand not the celebrity: if properly matched it can do wonders for the company, but it also has a number of potential problems like failure of celebrity in his profession, controversy, etc. LITERATURE REVIEW According to McCracken (1989), a celebrity could be defined as, Any individual who enjoys public recognition and who uses this recognition when they appear in the advertisement in front of the Consumers. There are multiple roles that a celebrity spokesperson may play (and the roles may not be mutually exclusive) (Kamen, Azhari and Kragh, 1975) in an advertisement such as that of a spokesperson, endorser, provider of a testimonial, or an actor. A spokesperson represents the company or brand like a salesman, while an endorser is associated with the brand even though he may not be an expert in the product category of the brand. In case of testimonials, the superiority of the product is attested by an individual or the personal experience of the celebrity. Lastly, the celebrity actor is only a character in a dramatic presentation in the advertisement. McCracken (1989) suggested four different modes of celebrity endorsers namely, Explicit mode, Implicit mode, Imperative mode, and the Co-present mode. In the explicit mode, the celebrity announces the endorsement of a product, while in the implicit mode; the celebrity uses verbal or physical communication for the product. In the imperative mode, the celebrity suggests the audience to use the endorsed product while the celebrity only appears with the product in the co-present mode. The studies of celebrity endorsements in the past 30 years have centered around two broad themes: source credibility and celebrity-brand congruence. Source credibility studies focus on the factors defining the credibility of a celebrity. Credibility of a celebrity has been found to be a major factor influencing consumer attitudes. Research has identified three dimensions of source credibility: attractiveness, expertise, and trustworthiness. Some of the studies (e.g., Ohanian, 1990) have used all the three dimensions to develop a scale that can measure credibility. On the other hand, there are studies that have analyzed only one or two dimensions of credibility and its impact on the consumer (Weiner and Mowen, 1986; Friedman and Friedman, 1979; Kamins and Gupta, 1994). However, the findings from these studies have been quite contradictory. While some studies have found trustworthiness to be the most important dimension of source credibility (McGinnies and Ward, 1980; Atkin and Block, 1983 and Kamins, 1989), others have emphasized attractiveness (Baker and Churchill, 1977; Kahle and Homer, 1985; Caballero et al., 1989; Silvera and Austad, 2004) or have suggested expertise (Maddux and Rogers, 1980; Ohanian, 1991) to be the most important parameter. Around 64 per cent of the commercials used the implicit mode of celebrity portrayal for different product categories. Usage of film celebrities was more extensive than sports celebrities in major product categories. This was probably because the shelf life of fame for a film celebrity is more than that of the sports celebrity. Male celebrities dominated the product categories like food and beverage, automobiles, and consumer durables. The female celebrities were featured majorly in beauty products. No distinct association was found between the product categories considered and the mode used for celebrity portrayal. (Jain et al. 2010) Using a celebrity for endorsement is not a new occurrence but prevalent since 19th century. Celebrity endorsements help to break the clutter and differentiate the brand. It also helps in image repair of a brand (Kaikati, 1987). In todays world where thousands of advertisements come across people in various forms, celebrity endorsement can easily win the confidence of consumers (Sabnavis, 2003). Celebrity helps in increasing profitability of the organization. In fact, celebrity endorsement is more effective than non-celebrity endorsement in generating attitudes towards advertisement (AAD), attitude towards brand (AB) and purchase intention (PI) (Erdogan, 1999). Research findings suggest that the percentage of celebrity advertisements out of the total number of ads aired is as high as 25-30% in western countries and around 60% in India (Patel, 2009). In such a scenario both academia and industry look for the issues in selection, use and effectiveness of celebrities as product endorsers. Research in celebrity endorsements in the last thirty years have tried to address various issues in celebrity endorsements such as the effects of credibility of endorser on the consumers (Friedman and Friedman, 1979; Goldsmith et al., 2000), issues in celebrity product match-up (Kamins, 1990; Till and Busler, 1998), meaning transfer in celebrity endorsements (McCracken, 1989) and a host of other issues such as effect of negative celebrity information, cross country comparison of celebrity advertising, gender and celebrity endorsement perceptions, etc. Celebrity endorsements is been accepted to be a ubiquitous feature of modern day marketing (McCracken 1989). It has also been seen that one quarter of all advertisement use/feature a celebrity to endorse a product or brand. This validates the effectiveness of Celebrity endorsements as a means of persuasive communication. It has the potential to enhance audience attentiveness, make the ad more memorable, credible, and desirable and add glamour to the endorsed product (Spielman, 1981). OBJECTIVES OF THIS STUDY The study is conducted to find out the impact of celebrity endorsement on rural consumers of Lucknow District. HYPOTHESIS OF THE STUDY The null hypothesis that there is no impact of celebrity endorsement on rural consumers was framed for the study. RESEARCH METHODOLOGY STUDY AREA The Study is conducted in the Lucknow city of Uttar Pradesh. Further, the respondents are selected from four different areas namely, Malihabad, Mohanlalganj, Banthara and Bakshi ka Talab of Lucknow. SAMPLING METHOD AND SAMPLE SIZE The sample method used to select the area for this study is random sampling technique. The sample method that was used to collect data from the population was convenience sampling. Sample size identified for the research is 300 respondents from Lucknow district. DATA COLLECTION The Study is based on Primary data and Secondary data both. The primary data is collected through structured questionnaire from the 300 respondents from Lucknow. The secondary data is collected through the magazines, journals, periodicals, people opinion and internet. ANALYTICAL TECHNIQUES Analytical Techniques are the statistical tools that are used for analyzing the collected data. The one sample t-test was used to test the hypothesis. ANOVA was used to find out the impact of celebrity on rural consumers. The SPSS 17 statistical software is also used for doing the calculations RESULTS AND DISCUSSIONS The study was conducted in rural areas of Lucknow. Using the random sampling technique the rural areas of Lucknow were selected. The study was done at Malihabad, Banthara, Bakshi ka Talab and Mohanlalganj. The total sample size targeted for study was 300 respondents from the selected areas but the responses were received from 277 respondents. The convenience sampling was used to collect the data from the respondents using structured questionnaires. The respondents were categorized in the age group 0- 10, 10- 20 and above 60, with the class interval of 10. It was found that maximum number of respondents were in the age group of 20- 30 with 67 respondents, followed by 10- 20 with 60 respondents as represented in Table 1. As per Table 2, the numbers of male respondents were 173 (62.5%) and the numbers of female respondents were 104 (37.5%). This shows that males participated the maximum in the study. Table 3 shows the preferences about the celebrities in the advertisements. The respondents are categorized in three categories name yes, no and cant say. The numbers of respondents who prefer the celebrities in the advertisements are 103 which contribute 37.2% of the responded population. Further, 96 respondents responded that they do not prefer celebrity in the advertisements which contribute to 34.7% of the responded population. 78 respondents replied cant say which is 28.2% of the responded population. Null Hypothesis: There is no impact of celebrity endorsement on rural consumers. Alternate Hypothesis: There is impact of celebrity endorsement on rural consumers. The null hypothesis indicates that there is no impact of celebrity endorsement on rural consumers, to test this hypothesis one-sample t-test is used, and as per the Table 4 the significance value is .000 which is significant at 5% level of significance. Hence the null hypothesis there is no impact of celebrity endorsement on rural consumers is rejected and alternate hypothesis there is impact of celebrity endorsement on rural consumers can be accepted. ANOVA was used to identify the impact of celebrity endorsement on rural consumers. Here age group of rural consumers is considered as dependent variable whereas prefer celebrity in advertisement is considered as Construct. There is a significant impact of celebrity endorsement on rural consumers. The value of significance level is .000, which is significant at 5% level of significance. Therefore, it can be said that there is an impact of celebrity endorsement on rural consumers based on the data collected for the study. CONCLUSION The statistical tools were used to determine the conclusion of the hypotheses framed. The tools used for analysis of the data are- frequency distribution, which showed the percentage by which the hypotheses has been accepted, one- sample t-test to test the hypotheses at 5% of significance and ANOVA to analyze the impact of celebrity endorsement on rural consumers. The following points were concluding observation to satisfy the objectives of the study and prove the hypotheses: 37.2% of the rural consumers prefer celebrities in the advertisements followed by 34.7% of rural consumers who do not prefer celebrities in the advertisements. There is an impact of celebrity endorsement on rural consumers as it is been proven in the study by calculating the significance level.

Monday, August 19, 2019

Financial Management Notes Essay -- GCSE Business Management Studies

ROLE OF FINANCIAL MANAGEMENT -  Ã‚  Ã‚  Ã‚  Ã‚  Financial management is one of the functions of management -  Ã‚  Ã‚  Ã‚  Ã‚  Financial management is concerned with o  Ã‚  Ã‚  Ã‚  Ã‚  Profits and losses of operations  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   o  Ã‚  Ã‚  Ã‚  Ã‚  Control over funds o  Ã‚  Ã‚  Ã‚  Ã‚  Ensuring appropriate cash flow is available o  Ã‚  Ã‚  Ã‚  Ã‚  Chas management o  Ã‚  Ã‚  Ã‚  Ã‚  Raising funds / controlling internal funds o  Ã‚  Ã‚  Ã‚  Ã‚  Investment of funds o  Ã‚  Ã‚  Ã‚  Ã‚  Cost control / pricing o  Ã‚  Ã‚  Ã‚  Ã‚  Forecasting / measuring financial performance against expectations -  Ã‚  Ã‚  Ã‚  Ã‚  Accounting is a subset of financial management. Financial transactions must be recorded, classified, stored and eventually reported to the managers. -  Ã‚  Ã‚  Ã‚  Ã‚  OBJECTIVES OF FINANCIAL MANAGEMENT o  Ã‚  Ã‚  Ã‚  Ã‚  Liquidity Refers to cash reserves being held, or to the ability to turn and investment into cash with little or no delay or loss of capital o  Ã‚  Ã‚  Ã‚  Ã‚  Solvency Refers to a business ability to pay its debts when due, and remain a going concern o  Ã‚  Ã‚  Ã‚  Ã‚  Profitability Refers to how profitable the business is from the perspectives of profit on sales, assets and shareholders equity o  Ã‚  Ã‚  Ã‚  Ã‚  Efficiency Examines how well working capital is managed, that is how quickly cash is collected from debtors, inventory sold and creditors paid. o  Ã‚  Ã‚  Ã‚  Ã‚  Growth Once a business is formed and operations commence, it enters a growth phase, where there should be an increase in the number of goods or services sold -  Ã‚  Ã‚  Ã‚  Ã‚  THE PLANNING CYCLE o  Ã‚  Ã‚  Ã‚  Ã‚  Strategic or corporate plans involve how the business can accomplish its objectives, generally to create a strong competitive advantage o  Ã‚  Ã‚  Ã‚  Ã‚  Organisational planning processes involve   Ã‚  Ã‚  Ã‚  Ã‚  The formulation of mission, goals and objectives,   Ã‚  Ã‚  Ã‚  Ã‚  An analysis of key environmental variables that present opportunities, threats, and constraints. It is known as an environmental audit   Ã‚  Ã‚  Ã‚  Ã‚  An organisational audit to evaluate strengths and weaknesses and identify where change needs to be met   Ã‚  Ã‚  Ã‚  The formulation of strategies within deadlines to achieve specific objectives   Ã‚  Ã‚  Ã‚  Ã‚  Monitoring and review to ensure that the mission is on target and that performance indicators are being met o  Ã‚  Ã‚  Ã‚  Ã‚  Tactical plans focus on the most efficient resource use by a business unit or department o  Ã‚  Ã‚  Ã‚  Ã‚  Operational plans are concerned with implementing the strategic plan through day to day processes, procedures, workflow and efficiency o  Ã‚  Ã‚  Ã‚  Ã‚  Financial plans represent the dollar quantification of the stra... ...e lease agreement come to an end. Here the emphasis is on rental, rather than what is effectively deferred purchase. †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  The lessee may be responsible for paying all or any of the maintenance, insurance operating costs etc ï‚ §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Factoring †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Is the selling of accounts receivable or debtors ledgers to a third party for less than the book value ï‚ §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Sale and leaseback †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Refers to a transaction in which the seller retains the use of an asset such as occupancy of a building, by simultaneously signing a lease, with the purchaser of the asset at the time of sale -  Ã‚  Ã‚  Ã‚  Ã‚  EFFECTIVE FINANCIAL PLANNING  Ã‚  Ã‚  Ã‚  Ã‚   o  Ã‚  Ã‚  Ã‚  Ã‚  EFFECTIVE CASHFLOW MANAGEMENT ï‚ §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Source of funds = use (application) of funds ï‚ §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Sources include †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Injection of new capital †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Raising new loans †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Reductions in stock ï‚ §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Applications include †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Pay out of loans †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Tax paid †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Purchase of fixed assets ï‚ §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Management strategies for cash flow problems include †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Shortening the operations cycle †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Increasing net profit margins †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Increasing trade payable †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Borrowing money †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Maintaining a minimum cash reserve

Sunday, August 18, 2019

Free College Essays - Influence of War in Knowles Separate Peace :: Separate Peace Essays

Influence of War as Shown in A Separate Peace Historical events can play an important role in a person’s life. In A Separate Peace, the whole atmosphere at the Devon School changed as World War II progressed. The boys either eagerly awaited draft, enlisted in the area of war they wanted, or did not want to go at all. The students at the school created new activities for enjoyment since the customary past times could not be played due to a lack of materials. When a friend â€Å"returns† from the war, the boys at Devon got a real sense of what the war was like. The boys learned that going to war was not all fun and games like they had anticipated. The influence World War II had on the characters in A Separate Peace and life at the Devon School, was clearly depicted through their actions and activities. The beginning of the novel allows the reader to get a feel of what the Devon School was like during that time period. Students of â€Å"war age† were constantly leaving Devon to go to the war, either by choice or by draft. Whether kids wanted to go or not, the anticipation was always present. As winter approached the Devon school, so was the encroaching shadow of the war. The boys were called out to help shovel free a troop train trapped by snow-blocked tracks. The experience "brings the war home" for all of them, and they realized they would have to face a crucial decision very soon. Maturity leaps upon them, whether they're ready for it or not, at the tender age of seventeen. The excitement of the war had gotten to everybody at the school, including the staff, and made it a chaotic place. The boys were able to get away with disobeying the rules. Many students cut class, and left school grounds often and were not penalized. When Leper â€Å"returned† from the war the boys realized that participating in the war wasn’t all fun and games, and that a lot of bad things happened. When Leper told Gene how he had been discharged on charges of insanity, Gene blew up at Leper. Gene had thought the war was a good place, and the notion of a Section Eight Discharge was not what he wanted to hear. It completely ruined Gene’s thoughts and his hopes.

Saturday, August 17, 2019

Barbados Revolt 1816 Essay

There were 2 main leaders of the Barbados Revolt of 1816, they were Bussa who was a free man in Africa and was brought to the Caribbean in the transatlantic slave trade which was indeed traumatizing. the other leader was Nanny Grigg. Causes The causes of the 1816 revolt in Barbados are: 1. The British Slave Trade was abolished in 1807 and the slaves mistook it for emancipation. There was a registry or registration bill or also called the registration of slaves {1812-1815} in which planters or owners had to register their slaves, this was passed so as to stop excessive punishment as well as the illegal sale of slaves. The planters were infuriated over the passing of this bill and saw it as interference in their domestic affairs. The slaves misinterpreted this as being angry about a plan for their emancipation. 2. A free colored man called Washington Franklin read newspaper reports of the anti-slavery debates. 3. Harsh treatment inflicted by white society-desire for permanent freedom and revenge. 4. Some slaves who were literate such as Nanny Grigg, had access to local and English newspapers from which they learnt about what was happening in England Haiti and elsewhere. 5. An able leader emerged among the slave that is Bussa, an African born slave. 6. This revolt was mainly fueled by the planters’ refusal to accept the Slave Registration Bill, the fact that the slaves felt their Emancipation was being withheld from them and the ideas of freedom and equality being cultivated in the minds of the slaves’ mind by non-conformists Missionaries. 7. The slaves believed emancipation had been granted, mistaking it for the Registration Bill (which stated that all slaves had to be accounted for, so no smuggling went on) and revolted. *Slaves in Barbados enjoyed some measure of freedom; this measure of freedom helped them to organize the revolt. Effects/Results 1. The missionaries were kicked out of Barbados – This help to turn the British public opinion against the planters and made people in Britain more favorable to emancipation – Humanitarians were encourage increasing their activity to bring down slavery 2. Planters became fearful 3. Several hundred slaves were killed Bussa Bussa, (also recorded as Bussa, or Busso or Bussoe) was born in Africa but captured and brought to Barbados to work as a slave on Bayleys Plantation in the southern parish of St Philip. (Today, the plantation’s ‘Great House’ is still standing and become the residence and recording studio of international musician Eddy Grant) His birth date remains unknown, however it is thought that he arrived in Barbados as an adult. On the plantation Bussa worked as a domestic slave, a head-ranger at Bayleys and did not experience the intense hardships that the field slaves endured. Domestic slaves generally considered themselves above the field slaves and some even exposed plans of slave rebellions to their ‘masters’ in order to gain favour. Bussa however, despite his ‘privileged’ position, helped to plan for months in advance. The slaves rebellions were born out of a strong desire to overthrow the oppressive white plantocracy and claim their freedom. It is said that plans for the rebellion began after the House of Assembly’s rejection of the Imperial Registry Bill in November 1815. On the night of Good Friday, April 12, 1816, the final preparations were made for the rebellion. At this meeting, it was decided that a mulatto slave Washington Francklyn was intended to become the Governor of the island. On the night of Good Friday, April 12, 1816, the final preparations were made for the rebellion. At this special meeting, it was decided that a mulatto slave Washington Francklyn was supposed to become the Governor of the island. On the morning of Sunday April 14, 1816 Bussa led around 400 slaves Several cane fields were set afire and from Bayley’s Plantation in St Philip the insurrection quickly spread to Christ Church, St George, St Thomas, St Lucy and St Thomas. The white plantation owners were totally caught off guard. The slaves fought valiantly against the troops of the First West India regiment and it was reported The rebellion spread from plantation to plantation until about half of the island was caught up in the insurrection. It took four days for the authorities to regain control. Bussa was killed in battle, and the ringleaders were executed. Although the rebellion ultimately failed, it was never forgotten. In 1985 more than a century later, the Emancipation Statue was erected at the roundabout in Haggatt Hall, St Michael. In 1999, Bussa was named as one of the national heroes of Barbados. and there is also a national holiday ‘Emancipation Day’, which celebrates the emancipation of the slaves.